Manuscripts / private access

Two manuscripts are under review.

These RNA-focused manuscripts form VHL’s current public research record and address questions relevant to its longer-term program. VHL does not publicly post full manuscripts while patent filing and peer review are in progress. Researchers may request a private copy by email. The listings below show only deliberately blurred previews.

PBISC BIBM full-paper review RNA-LLM BIBM review

Current manuscripts

Scope, status, and private-copy request.

Blurred preview of the PBISC manuscript first page

Blurred preview · full PDF not public

P–01 / PBISCBIBM full-paper review

PBISC: reference-free single-cell-resolution deconvolution of PBMC bulk RNA-seq

A generative method for producing analysis-ready PBMC pseudo-single-cell count matrices from bulk RNA-seq without a matched target-cohort single-cell reference at inference time.

Area: Cross-resolution transcriptomics
Input: PBMC bulk RNA-seq
Output: Pseudo-single-cell count matrix
Access: Private copy by email request

Blurred preview of the RNA-LLM manuscript first page

Blurred preview · full PDF not public

P–02 / RNA-LLMBIBM review

RNA-LLM: transcriptomes as one language-model token

A multimodal RNA-language model that compresses single-cell, pseudobulk, or bulk transcriptomes into one learned token for transcriptome-conditioned biological reasoning.

Area: RNA-language modeling
Input: Single-cell, pseudobulk, or bulk RNA
Representation: One learned RNA token
Access: Private copy by email request

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