Essays / research direction
Blog posts make the arguments, assumptions, and open questions behind VHL’s research agenda explicit. They state the author’s perspective and are not peer-reviewed findings.
Each essay is published as separate English and Korean editions.
For datasets, split definitions, model configurations, limitations, and corrections, use Technical Notes .
Latest essay
The latest essay examines the limits of group averages, the cost of exhaustive stratification, and the evidence an individual-response model would need before it could inform a real decision.
Individual-response models could help explore biological heterogeneity that finite trials cannot test exhaustively—if their predictions demonstrate prospective, calibrated value.
Seung Jun Lee · 14 August 2026 · 13 min readA model parameterized with one person’s biological measurements could eventually help compare responses to defined changes. RNA is where VHL has chosen to begin.
Seung Jun Lee · 13 August 2026 · 8 min readWhere to look
Readers should be able to tell whether they are reading an argument, a technical record, or a manuscript under review.
Author essays explain the reasoning behind the research direction and identify assumptions that still need to be tested.
Technical notes document provenance, methods, split design, negative results, limitations, and corrections.
Manuscript pages state scope and review status. Full copies remain private during patent filing and peer review.
Correspondence
Include the essay, claim, or research question you want to discuss. Do not send patient information, controlled-access data, or confidential material.
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